Is iMRS Prime backward compatible with iMRS?

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No. You cannot use the old iMRS applicators or iSLRS with the new iMRS Prime system for two reasons: (1) the interface connector is different and (2) the chip board and communicating protocol is entirely different. The iMORE finger sensor, however share the same connector interface, and it may still be used, though not officially supported by Swiss Bionic Solutions.